Evaluation of the QIAGEN CALR RGQ PCR Kit for the Detection of CALR Mutations in Suspected Myeloproliferative Neoplasms

H09; Category: Hematopathology

The CALR RGQ PCR Kit detects Type 1 and Type 2 mutations in CALR exon 9, as well as additional minor variants in this gene region. In order to evaluate this assay, the results of the CALR RGQ PCR Kit were compared to a preferred-method, laboratory-developed CALR exon 9 fragment size analysis assay in 146 samples. The results of the study show that QIAGEN’s CALR RGQ PCR Kit allows for efficient detection of CALR mutations with high analytical sensitivity and specificity.

Doyle L. et al.

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